Altered Levels of Acetylcholinesterase in Alzheimer Plasma
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چکیده
منابع مشابه
Altered Levels of Acetylcholinesterase in Alzheimer Plasma
BACKGROUND Many studies have been conducted in an extensive effort to identify alterations in blood cholinesterase levels as a consequence of disease, including the analysis of acetylcholinesterase (AChE) in plasma. Conventional assays using selective cholinesterase inhibitors have not been particularly successful as excess amounts of butyrylcholinesterase (BuChE) pose a major problem. PRINCI...
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Background: Recent studies have shown that oxidative stress (OS) is the most important indicator in the pathogenesis of Alzheimer's disease (AD), but the results in previous studies are conflicting. This study aimed to assess the plasma levels of 8-hydroxy-2'-deoxyguanosine (8-OHdG) as DNA oxidative damage marker and total antioxidant capacity (TAC) in patients with AD versus control group. ...
متن کاملPlasma testosterone levels in Alzheimer and Parkinson diseases.
BACKGROUND Testosterone deficiency, a treatable condition commonly seen in aging men, has been linked to Parkinson disease (PD) and Alzheimer disease (AD). In normal subjects, low testosterone levels are associated with cognitive and neuropsychiatric symptoms, yet the relationship between testosterone levels and cognitive function in PD and AD remains unclear. OBJECTIVE To examine the relatio...
متن کاملaltered plasma marker of oxidative dna damage and total antioxidant capacity in patients with alzheimer's disease
background: recent studies have shown that oxidative stress (os) is the most important indicator in the pathogenesis of alzheimer's disease (ad), but the results in previous studies are conflicting. this study aimed to assess the plasma levels of 8-hydroxy-2'-deoxyguanosine (8-ohdg) as dna oxidative damage marker and total antioxidant capacity (tac) in patients with ad versus control ...
متن کامل[Use of acetylcholinesterase inhibitors and memantine in Alzheimer-type dementia].
BACKGROUND The therapeutic options to treat Alzheimer-type dementia (ATD) in recent years, have made it increasingly necessary to become familiar with the employment pattern of these new medicinal products. METHODS A cross-sectional observational study of the population with ATD treated with acetylcholinesterase inhibitors and/or memantine in the Gallician Health Service. Databases were compi...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2010
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0008701